Diffusion lung imaging with hyperpolarized gas MRI
نویسندگان
چکیده
منابع مشابه
Functional lung imaging using hyperpolarized gas MRI.
The noninvasive assessment of lung function using imaging is increasingly of interest for the study of lung diseases, including chronic obstructive pulmonary disease (COPD) and asthma. Hyperpolarized gas MRI (HP MRI) has demonstrated the ability to detect changes in ventilation, perfusion, and lung microstructure that appear to be associated with both normal lung development and disease progres...
متن کاملImaging lung microstructure in mice with hyperpolarized 3He diffusion MRI.
Quantitative measurement of lung microstructure is of great significance in assessment of pulmonary disease, particularly in the earliest stages. The technique for MRI-based 3He lung morphometry was previously developed and validated for human lungs, and was recently extended to ex vivo mouse lungs. The technique yields accurate, quantitative information about the microstructure and geometry of...
متن کاملHyperpolarized gas MRI illuminates lung function
Historically, hope has been scant for catching any chronic occlusive pulmonary disease, including asthma and emphysema, early enough to treat and reverse, or at least stabilize, the condition. Today, optimism is being renewed that MR imaging with hyperpolarized noble gases will help diagnose lung airway disease at a treatable stage, assist in monitoring therapeutic progress, and help pharmaceut...
متن کاملQuantification of lung microstructure with hyperpolarized He diffusion MRI
Yablonskiy DA, Sukstanskii AL, Woods JC, Gierada DS, Quirk JD, Hogg JC, Cooper JD, Conradi MS. Quantification of lung microstructure with hyperpolarized He diffusion MRI. J Appl Physiol 107: 1258–1265, 2009. First published August 6, 2009; doi:10.1152/japplphysiol.00386.2009.—The structure and integrity of pulmonary acinar airways and their changes in different diseases are of great importance ...
متن کاملQuantification of lung microstructure with hyperpolarized 3He diffusion MRI.
The structure and integrity of pulmonary acinar airways and their changes in different diseases are of great importance and interest to a broad range of physiologists and clinicians. The introduction of hyperpolarized gases has opened a door to in vivo studies of lungs with MRI. In this study we demonstrate that MRI-based measurements of hyperpolarized (3)He diffusivity in human lungs yield qua...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: NMR in Biomedicine
سال: 2015
ISSN: 0952-3480
DOI: 10.1002/nbm.3448